Pharmaceutical industry , they have opted for the development of innovative drugs (biotech drugs ) to combat, alleviate or prevent diseases such as cancer, cardiovascular diseases, immune diseases, diseases of the central nervous system, the development of vaccines or the development of products to diagnose diseases inesem business school advanced course in medical affairs in the pharmaceutical industry more information drug design and development from the time a molecule is discovered until a drug is marketed, many years must pass.
This is so because the drug development process follows a long and complex process, subject to a very demanding legislation process and very strict quality standards. For this reason, it is worth remembering the different steps from the discovery of a new whatsapp number list molecule in a laboratory until the sale of a medicine is authorized. In this sense, the drug research and development process can be classified into four phases: 1) discovery phase . The discovery phase begins with the identification of a therapeutic target. Therapeutic targets are usually proteins that a priori can be the origin of a disease.
Thus, what is done in this phase is to analyze whether said substance really has a fundamental role in the development of the disease. Once the target has been validated, research is carried out into the manufacture of a drug to combat or modify it effectively and safely. 2) preclinical phase. Before testing a drug candidate in humans, it is mandatory to test laboratory tests and apply computer models to assess its safety, simulate its pharmacokinetic profile (absorption, distribution, metabolism, elimination in the body) and know its effect based on doses or places of action. This phase includes in vivo tests (living organisms) and in vitro tests (cells or tissues). 3) clinical phase . The clinical phase is carried out in humans whose objective is to
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